Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333426 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9TACR1 | |
| Bromide SCHEMBL7330456 | 0.99 | DPP4 (0.33) | DPP4DPP8DPP9TACR1 | |
| SCHEMBL7323929 | 0.83 | — | — | |
| SCHEMBL7265751 | 0.82 | TRHR (0.32) | — | |
| SCHEMBL7323922 | 0.81 | TRHR (0.37) | — | |
| SCHEMBL7325611 | 0.80 | — | — | |
| SCHEMBL7326055 | 0.79 | DPP4 (0.30) | DPP4DPP8DPP9 | |
| SCHEMBL7334480 | 0.78 | TRHR (0.38) | — | |
| SCHEMBL7325603 | 0.78 | TRHR (0.40) | — | |
| SCHEMBL7333371 | 0.78 | TRHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60172996-A | — | — | None | — | — | JP | disclosed |
| EP-0384380-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4636567-A | CNS DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-13 | — | — | US | disclosed |
| US-4610821-A | CENTRAL NERVOUS SYSTEM, THYROTROPIN RELEASING HORMONE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| US-4564609-A | NERVOUS SYSTEM DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| JP-S60172996-A | 2-AZETIDINONE-4-SUBSTITUTED COMPOUND AND ITS PREPARATION | YAMANOUCHI PHARMACEUT CO LTD | 1985-09-06 | — | — | JP | disclosed |
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |