Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272864 | 0.97 | L3MBTL1 (0.53) | L3MBTL1EPHX2FKBP1ARAB9ADPP4 | |
| SCHEMBL7272161 | 0.96 | L3MBTL1 (0.52) | L3MBTL1EPHX2FKBP1ARAB9ADPP4 | |
| SCHEMBL7267072 | 0.93 | DPP4 (0.59) | L3MBTL1EPHX2DPP4DPP8DPP7 | |
| SCHEMBL7266943 | 0.86 | DPP4 (0.56) | RAB9ADPP4DPP8DPP7MEN1 | |
| SCHEMBL10507283 | 0.86 | NPC1 (0.62) | EPHX2RAB9ADPP4PREPMEN1 | |
| SCHEMBL10507275 | 0.86 | NPC1 (0.62) | EPHX2RAB9ADPP4PREPMEN1 | |
| SCHEMBL10509401 | 0.85 | MEN1 (0.57) | RAB9ADPP4PREPMEN1NPC1 | |
| SCHEMBL10509400 | 0.85 | MEN1 (0.57) | RAB9ADPP4PREPMEN1NPC1 | |
| SCHEMBL7279154 | 0.84 | MEN1 (0.54) | EPHX2RAB9ADPP4PREPMEN1 | |
| SCHEMBL10506399 | 0.83 | MEN1 (0.56) | RAB9ADPP4PREPMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | claimed |
| EP-0268190-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0268190-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | claimed |