Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275190 | 0.97 | ITGB3 (0.44) | ITGB3ITGA2BS1PR1S1PR3LTA4H | |
| Hydrochloric Acid SCHEMBL7274645 | 0.91 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL7273468 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL7276387 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1F2F10 | |
| Hydrochloric Acid SCHEMBL7280291 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1F2F10 | |
| Hydrochloric Acid SCHEMBL7281006 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BLTA4HF2F10 | |
| Hydrochloric Acid SCHEMBL7283412 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BLTA4HF2F10 | |
| Hydrochloric Acid SCHEMBL7275028 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1F2F10 | |
| Water SCHEMBL8881986 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL7276103 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BS1PR1S1PR3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |