Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 5/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.37 |
| ▸ | USP14 | P54578 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274547 | 0.94 | CYP11B1 (0.45) | CYP11B1CYP11B2EP300SMOPANK3 | |
| SCHEMBL7282605 | 0.88 | CYP11B1 (0.50) | CYP11B1CYP11B2EP300USP14ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8571479 | 0.87 | CYP11B1 (0.49) | CYP11B1CYP11B2EP300USP14ALDH1A1 | |
| SCHEMBL7281169 | 0.84 | CYP11B1 (0.48) | CYP11B1CYP11B2EP300USP14ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7283690 | 0.82 | ITGB3 (0.43) | — | |
| SCHEMBL7272668 | 0.82 | CYP11B1 (0.46) | CYP11B1CYP11B2EP300ALDH1A1CYP3A4 | |
| SCHEMBL7274503 | 0.80 | CYP11B1 (0.43) | CYP11B1CYP11B2EP300USP14ALDH1A1 | |
| SCHEMBL7275719 | 0.79 | CYP11B1 (0.45) | CYP11B1CYP11B2EP300USP14ALDH1A1 | |
| SCHEMBL7275037 | 0.79 | CYP11B1 (0.42) | CYP11B1CYP11B2USP14ALDH1A1 | |
| SCHEMBL7273619 | 0.79 | CYP11B1 (0.42) | CYP11B1CYP11B2EP300USP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |