Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TRHR | P34981 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282352 | 0.90 | TRHR (0.43) | CAPN1TRHR | |
| SCHEMBL7282638 | 0.89 | TRHR (0.43) | TRHR | |
| SCHEMBL7273124 | 0.88 | TRHR (0.44) | TRHR | |
| SCHEMBL7272027 | 0.87 | TRHR (0.42) | TRHR | |
| SCHEMBL7278905 | 0.86 | TRHR (0.43) | TRHR | |
| SCHEMBL7272023 | 0.86 | ACE (0.43) | TRHR | |
| SCHEMBL7271987 | 0.85 | TRHR (0.42) | TRHR | |
| SCHEMBL7273569 | 0.85 | ACE (0.45) | TRHR | |
| SCHEMBL7271979 | 0.85 | TRHR (0.42) | TRHR | |
| SCHEMBL7274032 | 0.84 | ELANE (0.44) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | claimed |
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |