Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | TRHR | P34981 | 5/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272408 | 0.90 | TRHR (0.46) | TRHR | |
| SCHEMBL7273766 | 0.88 | TRHR (0.47) | TRHR | |
| SCHEMBL7429679 | 0.88 | TRHR (0.45) | TRHR | |
| SCHEMBL7276757 | 0.87 | TRHR (0.44) | ACETRHR | |
| SCHEMBL7281332 | 0.87 | TRHR (0.41) | TRHR | |
| SCHEMBL7273117 | 0.86 | TRHR (0.47) | TRHR | |
| SCHEMBL7282889 | 0.85 | TRHR (0.46) | TRHR | |
| SCHEMBL7271564 | 0.84 | TRHR (0.47) | TRHR | |
| SCHEMBL7273569 | 0.82 | ACE (0.45) | ACETRHRITGB3ITGA2B | |
| SCHEMBL7281074 | 0.81 | ACE (0.44) | ACETRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |