Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.45 |
| ▸ | F10 | P00742 | 11/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283112 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL7390938 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7282146 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7284058 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7280885 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7272547 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7275331 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7280939 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7282064 | 0.81 | F10 (0.52) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7276660 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BF10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |