Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283358 | 0.88 | — | — | |
| SCHEMBL7419226 | 0.86 | — | — | |
| SCHEMBL7293324 | 0.84 | — | — | |
| SCHEMBL7417012 | 0.75 | KMT2A (0.49) | ALDH1A1 | |
| SCHEMBL6556285 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL7274962 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL7293329 | 0.68 | — | — | |
| SCHEMBL7300249 | 0.67 | — | — | |
| SCHEMBL18343317 | 0.65 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL1825958 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649432-B1 | FLUORINE COMPRISING DIPEPTIDES AS INHIBITORS AGAINST HUMAN LEUCOCYTE ELASTASE INHIBITORS | ZENECA LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0652892-B1 | LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1997-08-20 | — | — | EP | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5532366-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-07-02 | — | — | US | disclosed |
| EP-0705100-A4 | THERAPEUTIC SUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0705100-A1 | THERAPEUTIC SUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0652892-A1 | LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY. | ZENECA LTD (GB) | 1995-05-17 | — | — | EP | disclosed |
| EP-0649432-A1 | FLUORINE COMPRISING DIPEPTIDES AS INHIBITORS AGAINST HUMAN LEUCOCYTE ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| US-5405852-A | Amide derivatives | ZENECA LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| WO-1994027591-A1 | THERAPEUTIC SUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| WO-1994001455-A1 | FLUORINE COMPRISING DIPEPTIDES AS INHIBITORS AGAINST HUMAN LEUCOCYTE ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |
| WO-1993024519-A1 | LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-12-09 | — | — | WO | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |