Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267303 | 1.00 | TAAR1 (0.49) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL7267306 | 1.00 | TAAR1 (0.49) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL7273903 | 0.83 | TAAR1 (0.54) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL7267743 | 0.83 | TAAR1 (0.54) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL7267749 | 0.83 | TAAR1 (0.54) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL15430652 | 0.79 | TAAR1 (0.56) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL15105333 | 0.78 | LMNA (0.55) | TAAR1SMN1; SMN2ALDH1A1LMNA | |
| Bicarbonate SCHEMBL7274197 | 0.76 | HDAC6 (0.55) | SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL12517126 | 0.76 | TAAR1 (0.53) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL13544593 | 0.76 | TAAR1 (0.53) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337348-B1 | Amides of cyclomethylen-1,2-bicarboxylic acids having therapeutical activity, processes for their preparation and pharmaceutical compositions containing them | GUIDOTTI & C SPA LABOR (IT) | 1994-02-02 | — | — | EP | claimed |