Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7273545 | 0.88 | MAPT (0.41) | ITGB3ITGA2BALDH1A1GAAPKM | |
| SCHEMBL7281133 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7280879 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7284822 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7272618 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7279862 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1S1PR1 | |
| SCHEMBL7284720 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7280721 | 0.80 | S1PR1 (0.54) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7276691 | 0.80 | ITGB3 (0.42) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL7281601 | 0.79 | ITGB3 (0.41) | ITGB3ITGA2BS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |