Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827421 | 0.89 | CYP19A1 (0.59) | TSHRCYP1A2CYP3A4NFKB1MEN1 | |
| SCHEMBL10782691 | 0.85 | MAPT (0.52) | KDM4ECYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL13754305 | 0.83 | KMT2A (0.50) | KDM4ETSHRCYP1A2MEN1KMT2A | |
| SCHEMBL20864387 | 0.82 | KMT2A (0.51) | KDM4ETSHRCYP1A2CYP3A4MEN1 | |
| SCHEMBL6289649 | 0.82 | KMT2A (0.51) | KDM4ETSHRMEN1KMT2ALMNA | |
| SCHEMBL8237704 | 0.81 | SMN1; SMN2 (0.48) | KDM4EMEN1KMT2ALMNAGABRA1 | |
| SCHEMBL5317776 | 0.81 | GAA (0.60) | KDM4ETSHRNFKB1MEN1KMT2A | |
| SCHEMBL2496245 | 0.80 | RAD52 (0.58) | KDM4ETSHRMEN1KMT2ALMNA | |
| SCHEMBL7273578 | 0.80 | ATM (0.66) | KDM4EATMTSHRCYP1A2CYP3A4 | |
| SCHEMBL10412025 | 0.79 | KMT2A (0.61) | KDM4EMEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375668-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1990-06-27 | — | — | EP | disclosed |
| US-4868306-A | Compounds | FISONS PLC (GB) | 1989-09-19 | — | — | US | disclosed |
| US-4791216-A | Para ethyl amino phenol pharmaceutical compounds | FISONS PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| US-4657929-A | Compounds | FISONS PLC (GB) | 1987-04-14 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |