Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289649 | 0.89 | KMT2A (0.51) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5317776 | 0.88 | GAA (0.60) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL27649299 | 0.88 | HSD17B1 (0.51) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL12720583 | 0.87 | KMT2A (0.64) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13754305 | 0.84 | KMT2A (0.50) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL20864387 | 0.83 | KMT2A (0.51) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7274262 | 0.81 | KDM4E (0.57) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10782691 | 0.81 | MAPT (0.52) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7417255 | 0.81 | CYP1A2 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL198282 | 0.80 | ALDH1A1 (0.62) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |