Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 9/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10797414 | 0.90 | ENPP1 (0.61) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL22291036 | 0.87 | ENPP1 (0.72) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL22407367 | 0.86 | ENPP1 (0.70) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL7276486 | 0.85 | ENPP1 (0.59) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| Hydrochloric Acid SCHEMBL10798406 | 0.84 | ENPP1 (0.58) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL22455025 | 0.82 | ENPP1 (0.66) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL20782445 | 0.80 | ENPP1 (0.74) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL27339358 | 0.79 | ACHE (0.58) | ENPP1MAPK1ACHEBACE1PDGFRB | |
| SCHEMBL20782729 | 0.79 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL22291145 | 0.79 | ENPP1 (0.69) | ENPP1MAPK1ACHEBACE1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668683-A | Cardiotonic quinazoline derivatives | KYOWA HAKKO KOGYO K.K. (JP) | 1987-05-26 | — | — | US | disclosed |
| EP-0195667-A2 | Cardiotonic quinazoline derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1986-09-24 | — | — | EP | disclosed |