⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170673 | 0.71 | — | — | |
| SCHEMBL6887929 | 0.69 | — | — | |
| SCHEMBL8718732 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL249480 | 0.67 | — | — | |
| SCHEMBL19285325 | 0.65 | — | — | |
| SCHEMBL2101285 | 0.65 | — | — | |
| SCHEMBL9052936 | 0.65 | — | — | |
| SCHEMBL1243288 | 0.65 | — | — | |
| SCHEMBL19285083 | 0.65 | — | — | |
| Ammonia Solution, Strong SCHEMBL4424705 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278173-B1 | Use of heterocyclic derivatives in the treatment of depressions | GLAXO GROUP LTD (GB) | 1993-11-03 | — | — | EP | claimed |
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |