Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | CTSL | P07711 | 2/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | CTSS | P25774 | 2/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.59 |
| ▸ | MDM4 | O15151 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | KYNU | Q16719 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402461 | 0.94 | ALDH1A1 (0.67) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL2420122 | 0.94 | ALDH1A1 (0.67) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL7294741 | 0.94 | ALDH1A1 (0.67) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL8569421 | 0.89 | ALDH1A1 (0.65) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL2406036 | 0.89 | ALDH1A1 (0.65) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL329686 | 0.89 | ALDH1A1 (0.74) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL7151822 | 0.89 | ALDH1A1 (0.74) | ALDH1A1ALOX15TSHRCTSLCTSB | |
| SCHEMBL9483283 | 0.88 | PPARG (0.67) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL9483288 | 0.88 | PPARG (0.67) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL7928050 | 0.87 | ALDH1A1 (0.72) | ALDH1A1ALOX15TSHRCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040317-A | AN ANTIAGGLOMERANTS USEFUL IN THE PREVENTION AND TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION | MERCK & CO., INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5658929-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0478363-B1 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO INC (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0743302-A2 | Sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5292756-A | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1993019046-A1 | NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-30 | — | — | WO | disclosed |
| EP-0478363-A2 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |