Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.79 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.79 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7282648 | 0.99 | ITGB3 (0.78) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Hydrochloric Acid SCHEMBL7284242 | 0.99 | ITGB3 (0.78) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Hydrochloric Acid SCHEMBL7276150 | 0.91 | ITGB3 (0.68) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL7276046 | 0.90 | ITGB3 (0.65) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8881415 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL7273988 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL7277517 | 0.90 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL9095006 | 0.90 | ITGB3 (0.65) | ITGB3ITGA2BPRSS1F2PLAU | |
| Hydrochloric Acid SCHEMBL7278229 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1 | |
| Hydrochloric Acid SCHEMBL7275270 | 0.89 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1TMPRSS2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | claimed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | claimed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | claimed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5677466-A | TESTING USING A AMIDINOPHENYL CONTAINING COMPOUND | DR. KARL THOMAE, GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0567967-B1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | THOMAE GMBH DR K (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0567967-A1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |