Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278384 | 1.00 | REN (0.51) | RENBDKRB2 | |
| SCHEMBL7281536 | 0.85 | REN (0.59) | RENBDKRB2 | |
| SCHEMBL7278514 | 0.85 | REN (0.59) | RENBDKRB2 | |
| SCHEMBL7278517 | 0.85 | REN (0.59) | RENBDKRB2 | |
| SCHEMBL9014796 | 0.83 | REN (0.56) | REN | |
| SCHEMBL9014885 | 0.83 | REN (0.56) | REN | |
| SCHEMBL9014952 | 0.76 | REN (0.69) | REN | |
| SCHEMBL9014956 | 0.76 | REN (0.69) | REN | |
| SCHEMBL9634502 | 0.76 | REN (0.69) | REN | |
| SCHEMBL9014908 | 0.76 | REN (0.75) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545838-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5098924-A | Hypotensive agents and angiotensin II inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0452587-A1 | Dihydroxy sulfonamide and sulfinamide renin inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-10-23 | — | — | EP | disclosed |