Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309284 | 1.00 | PRCP (0.61) | PRCPDPP7GAARAB9ASMN1; SMN2 | |
| SCHEMBL26716600 | 0.95 | PRCP (0.56) | PRCPDPP7GAARAB9ASMN1; SMN2 | |
| SCHEMBL14356206 | 0.91 | PRCP (0.67) | PRCPDPP7GAARAB9ASMN1; SMN2 | |
| SCHEMBL15329272 | 0.84 | PRCP (0.70) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL23746434 | 0.83 | PRCP (0.56) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL7268451 | 0.83 | PRCP (0.56) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL23746435 | 0.83 | PRCP (0.56) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL2794195 | 0.81 | PRCP (0.77) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL3289136 | 0.81 | PRCP (0.77) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL20061869 | 0.80 | PRCP (0.57) | PRCPDPP7TLR2HSD17B10HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077087-A2 | M24B AMINOPEPTIDASE INHIBITORS FOR CARDS INFLAMMASOME ACTIVATION | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-04-11 | — | — | WO | disclosed |
| US-20080187956-A1 | Modification at sulfatase motif of aldehyde tag through action of a formylglycine generating enzyme (FGE) generates formylglycine (FGly) residue | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-08-07 | — | — | US | disclosed |
| EP-0346847-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 1994-05-11 | — | — | EP | disclosed |
| EP-0346847-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-20 | — | — | EP | disclosed |