Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.67 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309284 | 0.91 | PRCP (0.61) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL7274579 | 0.91 | PRCP (0.61) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL26716600 | 0.86 | PRCP (0.56) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL16473202 | 0.83 | PRCP (0.64) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL6246208 | 0.83 | PRCP (0.88) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL7264385 | 0.83 | PRCP (0.88) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL7627030 | 0.82 | PRCP (0.63) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL15329272 | 0.82 | PRCP (0.70) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL23762418 | 0.81 | PRCP (0.97) | PRCPDPP7TLR2 | |
| SCHEMBL9232625 | 0.81 | PRCP (0.97) | PRCPDPP7TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291732-B2 | Isomeric fused pyrrolocarbazoles and isoindolones | CEPHALON, INC. (US) | 2007-11-06 | — | — | US | disclosed |