Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7275070 | 0.92 | DRD4 (0.42) | ITGB3ITGA2BF10PRSS1ITGAV | |
| SCHEMBL7284946 | 0.92 | F10 (0.48) | ITGB3ITGA2BF10PRSS1ITGAV | |
| Water SCHEMBL7271805 | 0.92 | DRD4 (0.41) | ITGB3ITGA2BF10ITGAV | |
| Hydrochloric Acid SCHEMBL7274910 | 0.91 | HTR1A (0.42) | ITGB3ITGA2BF10PRSS1ITGAV | |
| Hydrochloric Acid SCHEMBL7272974 | 0.90 | F10 (0.51) | ITGB3ITGA2BF10PRSS1ITGAV | |
| SCHEMBL7272267 | 0.90 | F10 (0.41) | ITGB3ITGA2BF10PRSS1ITGAV | |
| Water SCHEMBL7281948 | 0.90 | PPARG (0.41) | ITGB3ITGA2BF10ITGAVHTR1A | |
| SCHEMBL7275519 | 0.89 | HTR1A (0.44) | HTR1AOPRM1OPRD1 | |
| SCHEMBL7276363 | 0.89 | F10 (0.42) | ITGB3ITGA2BF10PRSS1ITGAV | |
| Water SCHEMBL7273367 | 0.89 | F10 (0.45) | ITGB3ITGA2BF10ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |