⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898157 | 1.00 | — | — | |
| SCHEMBL727479 | 1.00 | — | — | |
| SCHEMBL8899943 | 1.00 | NFKB1 (0.38) | — | |
| SCHEMBL3141284 | 0.76 | — | — | |
| SCHEMBL5832957 | 0.76 | — | — | |
| SCHEMBL10867683 | 0.76 | — | — | |
| SCHEMBL18709794 | 0.74 | — | — | |
| SCHEMBL19420224 | 0.74 | — | — | |
| SCHEMBL3014862 | 0.74 | — | — | |
| SCHEMBL14309251 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788485-A | Process for preparing antiviral agent | BRISTOL MYERS SQUIBB CO | 2015-07-22 | — | — | CN | claimed |
| JP-4726491-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| US-20060106215-A1 | Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | CHAN YEUNG Y | 2006-05-18 | — | — | US | claimed |
| US-20060106216-A1 | Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | PENDRI YADAGIRI R | 2006-05-18 | — | — | US | claimed |
| EP-1644384-A2 | PROCESS AND INTERMEDIATES FOR SYNTHESIS ENTECAVIR | Bristol-Myers Squibb Company (US) | 2006-04-12 | — | — | EP | claimed |
| JP-2006509800-A | — | — | 2006-03-23 | — | — | JP | claimed |
| US-20040192912-A1 | Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-30 | — | — | US | claimed |
| WO-2004052310-A2 | PROCESS AND INTERMEDIATES FOR SYNTHESIS ENTECAVIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | claimed |
| EP-0013620-A1 | Process for the peparation of 4-hydroxycyclopent-2-enone and derivatives | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1980-07-23 | — | — | EP | claimed |
| US-4132726-A | INTERMEDIATES FOR PROSTAGLANDIN COMPOUNDS | TEIJIN LIMITED (JP) | 1979-01-02 | — | — | US | claimed |
| JP-61040255-A | — | — | None | — | — | JP | disclosed |
| JP-1020091-A | — | — | None | — | — | JP | disclosed |
| JP-57159777-A | — | — | None | — | — | JP | disclosed |
| CN-104788485-B | The method for preparing antiviral agent | 百时美－施贵宝爱尔兰控股公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-104788485-A | Process for preparing antiviral agent | BRISTOL MYERS SQUIBB CO | 2015-07-22 | — | — | CN | disclosed |
| US-4061672-A | Derivatives of 9-hydroxy-13-trans-prostenoic acid | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061670-A | BRONCHODILATOR, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-RE29469-E | PROSTAGLANDINS; BRONCHODILATORS, HYPOTENSIVES, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-4028396-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3950406-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-04-13 | — | — | US | disclosed |