Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283507 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BCHEK2NQO2F2 | |
| SCHEMBL7282834 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BF2 | |
| SCHEMBL7273393 | 0.91 | ITGB3 (0.55) | ITGB3ITGA2BNQO2F2 | |
| Water SCHEMBL8882277 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BCHEK2F2 | |
| Hydrochloric Acid SCHEMBL7275699 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BCHEK2F9PARP10 | |
| SCHEMBL7275930 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BF2 | |
| SCHEMBL7275114 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7274865 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BF2 | |
| Hydrochloric Acid SCHEMBL7275664 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BF2 | |
| Hydrochloric Acid SCHEMBL7284546 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BCHEK2NQO2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |