Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274941 | 1.00 | CTSK (0.42) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7276789 | 0.93 | CTSK (0.41) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7276798 | 0.93 | CTSK (0.41) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7276468 | 0.91 | CTSK (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7276751 | 0.91 | CTSK (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7276756 | 0.91 | CTSK (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7278151 | 0.90 | CTSK (0.45) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7278159 | 0.90 | CTSK (0.45) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7268176 | 0.89 | CTSK (0.46) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7273511 | 0.88 | CTSK (0.44) | CTSKCTSSCYP3A4MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |