Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274973 | 1.00 | GAA (0.33) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL14666763 | 0.84 | ADH1B (0.38) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL9744380 | 0.81 | TSHR (0.37) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL2712968 | 0.81 | TSHR (0.37) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL9744375 | 0.81 | TSHR (0.37) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL4328796 | 0.81 | TSHR (0.37) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL647264 | 0.81 | TSHR (0.37) | GAATSHRCTSKCTSSEPHX1 | |
| Hydrochloric Acid SCHEMBL30546580 | 0.80 | TSHR (0.36) | GAATSHRCTSKCTSSEPHX1 | |
| SCHEMBL5131640 | 0.80 | BTK (0.36) | GAATSHRBTK | |
| SCHEMBL4996407 | 0.80 | BTK (0.36) | GAATSHRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1207300-A | — | — | None | — | — | JP | disclosed |
| JP-H01207300-A | DI-OR TRIPEPTIDE RENIN INHIBITORS CONTAINING LACTAM CONFORMATIONAL RESTRICTION IN ACHPA | MERCK & CO INC | 1989-08-21 | — | — | JP | disclosed |
| EP-0271041-A2 | Atrial peptide derivatives | ABBOTT LABORATORIES (US) | 1988-06-15 | — | — | EP | disclosed |