Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.65 |
| ▸ | CTSL | P07711 | 8/20 | 0.63 |
| ▸ | CTSB | P07858 | 5/20 | 0.63 |
| ▸ | CTSS | P25774 | 2/20 | 0.63 |
| ▸ | CTSK | P43235 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268325 | 0.90 | CTSL (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7268195 | 0.87 | CTSL (0.63) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10720515 | 0.85 | TACR1 (0.67) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10720521 | 0.85 | TACR1 (0.67) | TACR1CTSLCTSBCTSSCTSK | |
| Carbon Dioxide SCHEMBL2246839 | 0.84 | TACR1 (0.69) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7268180 | 0.82 | TACR1 (0.64) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL16095807 | 0.82 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL12052836 | 0.82 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10049956 | 0.82 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8100557 | 0.82 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |