SCHEMBL7275460

SCHEMBL7275460

CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7275457 1.00 REN (0.60) REN
SCHEMBL9844529 0.90 REN (0.58) REN
SCHEMBL9354237 0.90 REN (0.68) REN
SCHEMBL9354241 0.90 REN (0.68) REN
SCHEMBL7287419 0.89 REN (0.60) REN
SCHEMBL8909418 0.88 REN (0.58) REN
SCHEMBL9800529 0.88 REN (0.58) REN
SCHEMBL9724070 0.88 REN (0.51) REN
SCHEMBL9355302 0.87 REN (0.59) REN
SCHEMBL9355310 0.87 REN (0.59) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4963530-A Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-10-16 — — US disclosed
EP-0283970-A2 New peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-09-28 — — EP disclosed
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