Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631689 | 0.79 | NOX1 (0.39) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL5739509 | 0.76 | CYP2A6 (0.35) | KDM4ETDP1HSD17B10 | |
| SCHEMBL8556056 | 0.73 | GAA (0.46) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL3020352 | 0.70 | MAPT (0.47) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL29625260 | 0.70 | MAPT (0.47) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL3594659 | 0.67 | CA9 (0.53) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL2360570 | 0.67 | CA9 (0.53) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL6204345 | 0.67 | MEN1 (0.53) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL21575459 | 0.66 | — | — | |
| SCHEMBL2060618 | 0.66 | CA9 (0.51) | MEN1MAPTKMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963677-A | TREATMENT OF CONGESTIVE HEART FAILURE | ORION CORPORATION LTD. (FI) | 1990-10-16 | — | — | US | disclosed |
| EP-0322746-A1 | Heterocyclic compounds | ORION CORPORATION LIMITED (FI) | 1989-07-05 | — | — | EP | disclosed |