Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.50 |
| ▸ | CTSD | P07339 | 4/20 | 0.50 |
| ▸ | CTSE | P14091 | 4/20 | 0.47 |
| ▸ | PGA5 | P0DJD9 | 3/20 | 0.47 |
| ▸ | PGC | P20142 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268859 | 1.00 | REN (0.50) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7268982 | 0.92 | REN (0.52) | RENCTSDCTSE | |
| SCHEMBL9555039 | 0.90 | REN (0.50) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL9555026 | 0.90 | REN (0.50) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL9554410 | 0.87 | REN (0.49) | RENCTSDCTSE | |
| SCHEMBL9554405 | 0.87 | REN (0.49) | RENCTSDCTSE | |
| SCHEMBL9554977 | 0.87 | REN (0.53) | RENCTSDCTSEPGA5PGC | |
| SCHEMBL7268998 | 0.84 | REN (0.57) | REN | |
| SCHEMBL9555293 | 0.84 | REN (0.54) | RENCTSD | |
| SCHEMBL9554411 | 0.84 | REN (0.47) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391180-A2 | Peptide derivatives of amino acids having a renin-inhibiting effect | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-10 | — | — | EP | disclosed |