Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370866 | 0.94 | ACE (0.49) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5720655 | 0.91 | ACE (0.52) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3369568 | 0.91 | ACE (0.52) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL9022277 | 0.91 | ACE (0.52) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL7266839 | 0.88 | DPP4 (0.53) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL10882970 | 0.85 | ACE (0.50) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL11190870 | 0.83 | ACE (0.49) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL10882819 | 0.82 | ACE (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL11191259 | 0.82 | ACE (0.55) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL11195194 | 0.81 | ACE (0.52) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336368-B1 | N2-(1-carboxy-3-phenylpropyl)-L-lysine derivative and process of producing lysinopril using the compound | KANEGAFUCHI CHEMICAL IND (JP) | 1995-02-01 | — | — | EP | disclosed |