SCHEMBL9022277

SCHEMBL9022277

CCOC(=O)[C@H](CCc1ccccc1)OC(=O)C1CCCN1C(=O)C(N)CCCCNC(=O)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACE P12821 6/20 0.52
LMNA P02545 1/20 0.48
DPP4 P27487 1/20 0.47
DPP8 Q6V1X1 1/20 0.47
DPP9 Q86TI2 1/20 0.47
DPP7 Q9UHL4 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
F2 P00734 1/20 0.43
FKBP1A P62942 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5720655 1.00 ACE (0.52) ACELMNADPP4DPP8DPP9
SCHEMBL3369568 1.00 ACE (0.52) ACELMNADPP4DPP8DPP9
SCHEMBL3370866 0.92 ACE (0.49) ACEDPP4DPP8DPP9DPP7
SCHEMBL7275548 0.91 DPP4 (0.47) ACEDPP4DPP8DPP9DPP7
SCHEMBL3373798 0.89 DPP8 (0.43) ACELMNADPP4DPP8DPP9
SCHEMBL7266839 0.85 DPP4 (0.53) ACEDPP4DPP8DPP9DPP7
SCHEMBL3372067 0.85 PEPD (0.39) DPP4DPP8DPP9DPP7F2
SCHEMBL10885329 0.85 ACE (0.52) ACELMNADPP4DPP8DPP9
SCHEMBL3369068 0.82 SMN1; SMN2 (0.41) DPP8DPP7SMN1; SMN2
SCHEMBL5349213 0.82 SMN1; SMN2 (0.41) DPP8DPP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8253497-A None JP disclosed
JP-H08253497-A PEPTIDE-TYPE COMPOUND RICHTER GEDEON V G RT 1996-10-01 JP disclosed