Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266946 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6HTTTAAR1LMNA | |
| SCHEMBL7266949 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6HTTTAAR1LMNA | |
| SCHEMBL7267858 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6HTTTAAR1LMNA | |
| SCHEMBL7267865 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6HTTTAAR1LMNA | |
| SCHEMBL7267962 | 0.83 | KDM4E (0.44) | HTTTAAR1LMNARAB9AGAA | |
| SCHEMBL7267957 | 0.83 | KDM4E (0.44) | HTTTAAR1LMNARAB9AGAA | |
| SCHEMBL7267955 | 0.83 | KDM4E (0.44) | HTTTAAR1LMNARAB9AGAA | |
| Bicarbonate SCHEMBL7274222 | 0.82 | HTT (0.55) | HDAC1HDAC6HTTLMNARAB9A | |
| SCHEMBL9682555 | 0.79 | HTT (0.46) | HTTTAAR1LMNARAB9AGAA | |
| SCHEMBL9682559 | 0.79 | HTT (0.46) | HTTTAAR1LMNARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337348-B1 | Amides of cyclomethylen-1,2-bicarboxylic acids having therapeutical activity, processes for their preparation and pharmaceutical compositions containing them | GUIDOTTI & C SPA LABOR (IT) | 1994-02-02 | — | — | EP | claimed |