Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682564 | 1.00 | HTT (0.46) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL9682555 | 1.00 | HTT (0.46) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL14398146 | 0.85 | HTT (0.45) | HTTRAB9AALDH1A1GPR88MEN1 | |
| SCHEMBL8303697 | 0.82 | HTT (0.61) | HTTMAPTRAB9ALMNAALDH1A1 | |
| SCHEMBL7267865 | 0.79 | HDAC1 (0.45) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL7275871 | 0.79 | HDAC1 (0.45) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL7266946 | 0.79 | HDAC1 (0.45) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL7266949 | 0.79 | HDAC1 (0.45) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL7267858 | 0.79 | HDAC1 (0.45) | HTTTAAR1MAPTRAB9ALMNA | |
| SCHEMBL7267957 | 0.78 | KDM4E (0.44) | HTTTAAR1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095137-A | Hypotensives | LABORATORI GUIDOTTI SPA (IT) | 1992-03-10 | — | — | US | disclosed |