Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270768 | 0.85 | DRD2 (0.51) | DRD2HTR2ASLC6A4HRH1HTR3A | |
| SCHEMBL7274861 | 0.85 | DRD2 (0.51) | DRD2HTR2ASLC6A4HRH1HTR3A | |
| Hydrochloric Acid SCHEMBL7270776 | 0.83 | DRD2 (0.50) | DRD2HTR2ASLC6A4HRH1HTR3A | |
| SCHEMBL1548735 | 0.80 | NOTUM (0.42) | DRD2HCRTR1HCRTR2SLC5A2HTR2A | |
| SCHEMBL7270927 | 0.78 | GLA (0.52) | DRD2HTR2ASLC6A4HRH1HTR3A | |
| SCHEMBL1338411 | 0.78 | MYC (0.43) | HCRTR1HCRTR2TDP1KDM4EALDH1A1 | |
| SCHEMBL27946840 | 0.77 | HTR2A (0.57) | HCRTR1HCRTR2SLC5A2HTR2ASLC6A4 | |
| SCHEMBL24104598 | 0.76 | KDM4E (0.36) | DRD2KDM4EALDH1A1 | |
| SCHEMBL31115471 | 0.76 | KDM4E (0.36) | DRD2KDM4EALDH1A1 | |
| SCHEMBL7276117 | 0.76 | DRD2 (0.59) | DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |