Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PARL | Q9H300 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847739 | 0.81 | TDP1 (0.46) | CA2CA12ENPP3ENPP1KMT2A | |
| Benzofuran SCHEMBL27939490 | 0.78 | CTNNB1 (0.49) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL27939489 | 0.78 | CTNNB1 (0.49) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL3892079 | 0.76 | CTNNB1 (0.47) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL11121745 | 0.76 | CTNNB1 (0.50) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL6244470 | 0.76 | CTNNB1 (0.50) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL11121861 | 0.76 | CTNNB1 (0.50) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL8100958 | 0.74 | MAOA (0.42) | CA2CA12MAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL3898681 | 0.74 | CTNNB1 (0.45) | CA2CA12MAOBCTNNB1WNT3A | |
| SCHEMBL19810089 | 0.74 | TSHR (0.48) | CA2CA12KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302793-B1 | Aralkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI ELF (FR) | 1993-12-15 | — | — | EP | disclosed |
| US-5215988-A | Treating angina, hypertension, arrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-06-01 | — | — | US | disclosed |
| EP-0302793-A2 | Aralkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | ELF SANOFI (FR) | 1989-02-08 | — | — | EP | disclosed |