Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294835 | 0.85 | MAPT (0.51) | CCR6ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL7267124 | 0.82 | PDE3B (0.41) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL7267606 | 0.77 | MAPT (0.60) | ALDH1A1HTTTDP1L3MBTL1CYP2C9 | |
| SCHEMBL7267653 | 0.76 | PDE4A (0.45) | ALDH1A1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL10760147 | 0.75 | MAPT (0.53) | ALDH1A1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL10669006 | 0.68 | EPHX1 (0.56) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL11703472 | 0.68 | PDE3B (0.49) | ALDH1A1L3MBTL1MAPTTP53SMN1; SMN2 | |
| SCHEMBL2153289 | 0.67 | CCR6 (1.00) | CCR6ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL2153976 | 0.67 | MAPT (0.70) | CCR6ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL7273670 | 0.67 | PDE3B (0.50) | MAPTLMNASMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339208-B1 | 6-Oxopyridazine derivatives, process for their preparation and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-4968683-A | INOTROPIC, CARDIOTONIC | HEUMANN PHARMA GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0339208-A1 | 6-Oxopyridazine derivatives, process for their preparation and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1989-11-02 | — | — | EP | disclosed |