Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267653 | 0.83 | PDE4A (0.45) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7267606 | 0.83 | MAPT (0.60) | PDE3BPDE3AGPR119GAAALDH1A1 | |
| SCHEMBL10760147 | 0.82 | MAPT (0.53) | PDE3BPDE3AGPR119GAAALDH1A1 | |
| SCHEMBL7276174 | 0.82 | CCR6 (0.51) | GAAALDH1A1PKML3MBTL1MAPT | |
| SCHEMBL7299404 | 0.82 | GALR3 (0.62) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10333086 | 0.74 | MAPT (0.59) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11703472 | 0.74 | PDE3B (0.49) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7273670 | 0.73 | PDE3B (0.50) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7273841 | 0.72 | PDE3B (0.49) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11634895 | 0.72 | PDE3B (0.49) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339208-B1 | 6-Oxopyridazine derivatives, process for their preparation and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-4968683-A | INOTROPIC, CARDIOTONIC | HEUMANN PHARMA GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0339208-A1 | 6-Oxopyridazine derivatives, process for their preparation and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1989-11-02 | — | — | EP | disclosed |