Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PHGDH | O43175 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277610 | 0.89 | PHGDH (0.55) | RAB9AGAAPHGDHNPC1HDAC1 | |
| SCHEMBL13529663 | 0.82 | PHGDH (0.62) | RAB9AGAAPHGDHNPC1HDAC1 | |
| SCHEMBL13529610 | 0.81 | KMT2A (0.50) | RAB9AGAAPHGDHNPC1HDAC1 | |
| SCHEMBL7284215 | 0.78 | POLB (0.54) | RAB9AGAANPC1HDAC1SMN1; SMN2 | |
| SCHEMBL25877853 | 0.78 | MEN1 (0.73) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL641989 | 0.75 | PHGDH (0.77) | RAB9AGAAPHGDHNPC1HDAC1 | |
| SCHEMBL7278132 | 0.75 | PHGDH (0.68) | RAB9AGAAPHGDHNPC1HDAC1 | |
| SCHEMBL10376329 | 0.73 | PHGDH (0.70) | RAB9AGAAPHGDHNPC1HDAC1 | |
| SCHEMBL13870767 | 0.72 | KMT2A (0.57) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13110888 | 0.72 | PHGDH (0.68) | RAB9AGAAPHGDHNPC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137918-A | Anticancer agent | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0242851-A1 | N-(2'-aminophenyl)-benzamide derivatives, process for their manufacture and their application in the treatment of neoplastic illness | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1987-10-28 | — | — | EP | disclosed |