Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958604 | 0.89 | PHGDH (0.76) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL27847056 | 0.87 | PHGDH (0.74) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL10354307 | 0.87 | NPC1 (0.74) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL28793942 | 0.86 | PHGDH (0.64) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL1335449 | 0.86 | POLB (1.00) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL4251730 | 0.85 | MAPT (1.00) | POLBRAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL10376329 | 0.85 | PHGDH (0.70) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL2414416 | 0.85 | PHGDH (0.70) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL6169544 | 0.85 | NPC1 (0.78) | PHGDHPOLBRAB9ANPC1MAPT | |
| SCHEMBL175272 | 0.84 | MEN1 (0.71) | PHGDHPOLBRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121293160-A | Simple preparation method of benzimidazole compound | 浙江科技大学 | 2026-01-09 | — | — | CN | disclosed |
| CN-109836378-B | Sphingomyelin synthase inhibitor, preparation method and application thereof | 上海华汇拓医药科技有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-110041272-B | 2- (2-chlorphenyl) quinazoline-4 (3H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-30 | — | — | CN | disclosed |
| CN-110041273-B | 2- (2-chloro-4-methylphenyl) quinazoline-4 (3H) -ketone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-20 | — | — | CN | disclosed |
| CN-110041272-A | 2- (2- chlorphenyl) quinazoline -4 (3H) -one analog derivative and its preparation method and application | 中国人民解放军军事科学院军事医学研究院 | 2019-07-23 | — | — | CN | disclosed |
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9067955-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon—carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-30 | — | — | US | disclosed |
| US-9067955-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon—carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-30 | — | — | US | disclosed |
| US-9067955-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon—carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-30 | — | — | US | disclosed |
| US-6630598-B2 | Reacting nitroaniline compound with acid chloride/anhydride in presence of alkali metal/earth metal compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-07 | — | — | US | disclosed |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-03 | — | — | US | disclosed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | disclosed |
| US-20020016506-A1 | Process for producing N-acylnitroaniline derivative | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-02-07 | — | — | US | disclosed |
| EP-1172356-A1 | Process for producing N-acylnitroaniline derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0662074-A1 | PROCESS FOR PREPARING P-NITROAROMATIC AMIDES AND PRODUCTS THEREOF. | MONSANTO CO (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1993024447-A1 | PROCESS FOR PREPARING P-NITROAROMATIC AMIDES AND PRODUCTS THEREOF | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| EP-0232972-B1 | NEGATIVE PHOTORESIST COMPOSITIONS AND PROCESSES FOR PREPARING THERMALLY STABLE, NEGATIVE IMAGES USING THEM | ROHM AND HAAS COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0232972-A2 | Negative photoresist compositions and processes for preparing thermally stable, negative images using them | ROHM AND HAAS COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4074046-A | REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016506-A1 | Process for producing N-acylnitroaniline derivative | NAAA, NAT1, ACOT7 | PHGDH 952/4885POLB 3496/4885RAB9A 1690/4885 |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | PHGDH 2532/4885POLB 3522/4885RAB9A 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.