Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292968 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7287855 | 0.91 | ITGB3 (0.52) | ITGB3ITGA2BPREP | |
| SCHEMBL7331961 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7342979 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7296887 | 0.89 | PREP (0.43) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7286805 | 0.89 | PREP (0.43) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7295450 | 0.89 | PREP (0.45) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7277836 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7277827 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BPREPPLA2G10PLA2G5 | |
| SCHEMBL7295402 | 0.89 | MAPT (0.42) | ITGB3ITGA2BPREPPLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529858-B1 | 2-Piperazinone compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5294713-A | Inhibiting cell adhesion | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0529858-A1 | 2-Piperazinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |