Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532199 | 0.90 | ADORA2B (0.65) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL30438436 | 0.90 | ADORA2B (0.65) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL30438203 | 0.81 | KDM4E (0.62) | ADORA2BADORA2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28909317 | 0.81 | KDM4E (0.62) | ADORA2BADORA2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL661108 | 0.79 | ADORA2B (1.00) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8872400 | 0.79 | ADORA2B (0.69) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7270306 | 0.76 | ADORA2B (0.64) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8879577 | 0.76 | ADORA2B (0.60) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8872884 | 0.75 | ADORA2B (0.65) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL14564546 | 0.73 | ADORA2B (0.79) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415456-B1 | Xanthine compounds | KYOWA HAKKO KOGYO KK (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5525607-A | DIURETICS, BRONCHODILATORS, RENAL PROTECTING AGENTS | KYOWA HAKKO KOGYO CO., LTD (JP) | 1996-06-11 | — | — | US | disclosed |
| US-5290782-A | Bronchodilator agents, diuretics for renal protective agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0415456-A2 | Xanthine compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |