Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | PREP | P48147 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952307 | 0.88 | PRCP (0.68) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL953206 | 0.87 | KMT2A (0.69) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL953204 | 0.87 | KMT2A (0.69) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL10763737 | 0.87 | PRCP (0.82) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL7273208 | 0.87 | PRCP (0.82) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL12234864 | 0.86 | KMT2A (0.65) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL10954962 | 0.86 | PRCP (0.75) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL9564578 | 0.86 | KMT2A (0.67) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL10369207 | 0.86 | KMT2A (0.70) | PRCPNPSR1KMT2AALDH1A1TSHR | |
| SCHEMBL9564581 | 0.86 | KMT2A (0.67) | PRCPNPSR1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505868-B1 | N-Acyl-alpha-aminoacids derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-13 | — | — | EP | disclosed |
| EP-0505868-A2 | N-Acyl-alpha-aminoacids derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-09-30 | — | — | EP | disclosed |