Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546764 | 0.86 | HDAC3 (0.68) | HDAC3HDAC1HDAC8NCOR2MEN1 | |
| SCHEMBL7399072 | 0.86 | MAPT (0.61) | MEN1KMT2AL3MBTL1DRD2KDM4E | |
| Hydrochloric Acid SCHEMBL8824760 | 0.84 | MAPT (0.60) | MEN1KMT2ADRD2KDM4ENOTUM | |
| SCHEMBL8605349 | 0.83 | TMEM97 (0.49) | HDAC3HDAC1HDAC8NCOR2MEN1 | |
| SCHEMBL8607230 | 0.80 | DRD2 (0.53) | MEN1KMT2ADRD2KDM4EHTR1A | |
| SCHEMBL3477555 | 0.79 | HDAC3 (0.70) | HDAC3HDAC1HDAC8NCOR2MEN1 | |
| SCHEMBL9718777 | 0.78 | HRH1 (0.54) | MEN1KMT2ADRD2NOTUMHTR1A | |
| SCHEMBL3891857 | 0.78 | HDAC3 (0.68) | HDAC3HDAC1HDAC8NCOR2MEN1 | |
| SCHEMBL22248030 | 0.78 | NOTUM (0.66) | MEN1KMT2AL3MBTL1USP2KDM4E | |
| SCHEMBL4210440 | 0.77 | GAA (0.53) | MEN1KMT2AUSP2KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411751-A1 | Renin inhibitory peptides | Beecham Group p.l.c. (GB) | 1991-02-06 | — | — | EP | disclosed |