Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7277321 | 0.99 | ITGB3 (0.61) | ITGB3ITGA2BGPR119RXFP1CHEK2 | |
| SCHEMBL7277517 | 0.91 | ITGB3 (0.65) | ITGB3ITGA2BGPR119RXFP1IRAK4 | |
| Hydrochloric Acid SCHEMBL7284744 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BRXFP1IRAK4DGAT1 | |
| Hydrochloric Acid SCHEMBL7277371 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BCHEK2IRAK4 | |
| SCHEMBL9261874 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BGPR119RXFP1IRAK4 | |
| Hydrochloric Acid SCHEMBL7285261 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BRXFP1IRAK4MAPT | |
| Hydrochloric Acid SCHEMBL7287064 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BGPR119RXFP1IRAK4 | |
| SCHEMBL7277434 | 0.88 | ITGB3 (0.80) | ITGB3ITGA2BRXFP1IRAK4DGAT1 | |
| Hydrochloric Acid SCHEMBL7285424 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BGPR119IRAK4DGAT1 | |
| Hydrochloric Acid SCHEMBL7278436 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BRXFP1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |