Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286371 | 0.88 | ELANE (0.71) | ELANE | |
| SCHEMBL9011673 | 0.88 | ELANE (0.83) | ELANE | |
| Hydrochloric Acid SCHEMBL7283633 | 0.88 | ELANE (0.70) | ELANE | |
| SCHEMBL7445358 | 0.83 | ELANE (0.65) | ELANE | |
| SCHEMBL7276755 | 0.82 | ELANE (0.77) | ELANE | |
| SCHEMBL9011669 | 0.81 | ELANE (0.62) | ELANE | |
| SCHEMBL7274370 | 0.79 | ELANE (1.00) | ELANE | |
| SCHEMBL7284369 | 0.78 | ELANE (1.00) | ELANE | |
| SCHEMBL7285137 | 0.77 | ELANE (0.90) | ELANE | |
| SCHEMBL7439568 | 0.77 | ELANE (0.81) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |