Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 5/20 | 0.43 |
| ▸ | METAP1 | P53582 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278692 | 0.98 | REN (0.46) | RENMETAP2METAP1TP53 | |
| SCHEMBL8203573 | 0.98 | REN (0.46) | RENMETAP2METAP1TP53 | |
| SCHEMBL5709598 | 0.87 | REN (0.44) | RENMETAP2METAP1 | |
| SCHEMBL5709564 | 0.87 | REN (0.44) | RENMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL9848324 | 0.86 | REN (0.47) | RENMETAP2METAP1TP53 | |
| SCHEMBL9189973 | 0.86 | REN (0.39) | RENMETAP2METAP1 | |
| SCHEMBL10715820 | 0.85 | REN (0.43) | RENMETAP2METAP1 | |
| SCHEMBL10713175 | 0.85 | REN (0.43) | RENMETAP2METAP1 | |
| SCHEMBL10712125 | 0.85 | REN (0.43) | RENMETAP2METAP1 | |
| SCHEMBL12507498 | 0.84 | REN (0.49) | RENMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491132-A | HYPOTENSIVE AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0476515-A1 | New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |