Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699458 | 1.00 | CASP1 (0.48) | CASP1 | |
| SCHEMBL5197347 | 1.00 | CASP1 (0.48) | CASP1 | |
| SCHEMBL17919265 | 0.88 | CASP1 (0.40) | CASP1 | |
| SCHEMBL9697843 | 0.84 | CASP1 (0.49) | CASP1 | |
| SCHEMBL9697658 | 0.84 | CASP1 (0.49) | CASP1 | |
| SCHEMBL9697634 | 0.84 | CASP1 (0.49) | CASP1 | |
| SCHEMBL646877 | 0.84 | CASP1 (0.40) | CASP1 | |
| SCHEMBL645196 | 0.80 | CASP1 (0.45) | CASP1 | |
| SCHEMBL3471522 | 0.79 | SMN1; SMN2 (0.44) | CASP1 | |
| SCHEMBL9697657 | 0.78 | CASP1 (0.42) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519748-B1 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO INC (US) | 1998-09-02 | — | — | EP | disclosed |