Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | MASP2 | O00187 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283894 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BMASP2PPARGFLT1 | |
| SCHEMBL7282413 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BMASP2IRAK4MAPT | |
| SCHEMBL7277659 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BMASP2IRAK4PPARG | |
| SCHEMBL7285055 | 0.91 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4MAPTDGAT1 | |
| SCHEMBL7337066 | 0.91 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4MAPTDGAT1 | |
| SCHEMBL7275389 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BMASP2MAPTL3MBTL1 | |
| SCHEMBL7277377 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BIRAK4RXFP1 | |
| SCHEMBL7275398 | 0.86 | ITGB3 (0.40) | ITGB3ITGA2BMASP2PPARG | |
| SCHEMBL7278638 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BMASP2IRAK4MAPT | |
| SCHEMBL7283682 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BMASP2IRAK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |