Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859251 | 0.85 | ACE (0.52) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL7859254 | 0.85 | ACE (0.52) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL1748990 | 0.83 | ACE (0.53) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL1748989 | 0.83 | ACE (0.53) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL9304565 | 0.82 | ACE (0.49) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL27207410 | 0.82 | ACE (0.52) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL5153113 | 0.82 | ACE (0.52) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL9501257 | 0.82 | ACE (0.49) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL27203736 | 0.82 | ACE (0.52) | ACESCN9AITGB3ITGA2BPTPN1 | |
| SCHEMBL25183090 | 0.81 | ACE (0.51) | ACESCN9AITGB3ITGA2BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |