Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 1.00 |
| ▸ | MMP3 | P08254 | 2/20 | 0.74 |
| ▸ | MMP9 | P14780 | 2/20 | 0.74 |
| ▸ | MMP2 | P08253 | 1/20 | 0.74 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278285 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 | |
| SCHEMBL9650310 | 0.93 | MMP1 (0.86) | MMP1MMP3MMP9ADAM17 | |
| SCHEMBL7275835 | 0.92 | MMP1 (1.00) | MMP1MMP3MMP9ADAM17 | |
| SCHEMBL7276467 | 0.92 | MMP1 (1.00) | MMP1MMP3MMP9ADAM17 | |
| SCHEMBL7284853 | 0.92 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 | |
| SCHEMBL7284842 | 0.92 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 | |
| SCHEMBL7615629 | 0.91 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 | |
| SCHEMBL7615635 | 0.91 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 | |
| SCHEMBL7275874 | 0.90 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 | |
| SCHEMBL7275866 | 0.90 | MMP1 (1.00) | MMP1MMP3MMP9MMP2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273689-B1 | DERIVATIVES OF N-(2-ALKYL-3-MERCAPTO-GLUTARYL) ALPHA-AMINO ACIDS AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1991-11-27 | — | — | EP | claimed |
| EP-0273689-A2 | Derivatives of N-(2-alkyl-3-mercapto-glutaryl) alpha-amino acids and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1988-07-06 | — | — | EP | claimed |
| US-5109000-A | THIOL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITOR | BEECHAM GROUP P.L.C. (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0273689-B1 | DERIVATIVES OF N-(2-ALKYL-3-MERCAPTO-GLUTARYL) ALPHA-AMINO ACIDS AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1991-11-27 | — | — | EP | disclosed |
| US-4937243-A | TREATING CONNECTIVE TISSUE DISEASES | BEECHAM GROUP P.L.C. (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0273689-A2 | Derivatives of N-(2-alkyl-3-mercapto-glutaryl) alpha-amino acids and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1988-07-06 | — | — | EP | disclosed |