SCHEMBL7278345

SCHEMBL7278345

OCCCCCc1ccco1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
CYP3A4 P08684 1/20 0.59
ALOX15 P16050 1/20 0.59
USP2 O75604 1/20 0.59
HPGD P15428 1/20 0.59
CHRM2 P08172 1/20 0.44
KMT2A Q03164 2/20 0.44
EPHX2 P34913 3/20 0.42
ALOX5 P09917 1/20 0.38
KCNH3 Q9ULD8 1/20 0.38
HTR2B P41595 1/20 0.37
GLS O94925 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11354590 1.00 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL16124244 1.00 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL9508203 1.00 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL30252278 1.00 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL2231148 0.98 ALDH1A1 (0.56) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL837175 0.91
Acetic Acid SCHEMBL9705698 0.89 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL7093157 0.89 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4ALOX15USP2
SCHEMBL7094868 0.87 ALDH1A1 (0.67) ALDH1A1TDP1CYP3A4ALOX15USP2
1,5-Pentanediol SCHEMBL29013568 0.85 CHRM2 (0.46) ALDH1A1TDP1CYP3A4ALOX15USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112672990-A Catalyst for producing 1, 2-pentanediol, and method for producing 1, 2-pentanediol using the catalyst 韩国化学研究院 2021-04-16 CN disclosed
EP-0322164-B1 ETHANOLAMINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-09-22 EP disclosed
EP-0543936-A4 RENIN INHIBITORS 1993-06-30 EP disclosed
EP-0543936-A1 RENIN INHIBITORS ABBOTT LABORATORIES (US) 1993-06-02 EP disclosed
EP-0207454-B1 ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS STERLING WINTHROP INC. (US) 1992-09-09 EP disclosed
US-5039697-A Adrenergic stimulants, bronchodilators GLAXO GROUP LIMITED (GB) 1991-08-13 US disclosed
US-5032609-A Ethanolamine derivatives GLAXO GROUP LIMITED (GB) 1991-07-16 US disclosed
US-5002966-A Adrenergic Stimulants GLAXO GROUP LIMITED (GB) 1991-03-26 US disclosed
EP-0376040-A2 N-phosphinyl di-and tripeptides as renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP disclosed
US-4861791-A Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents STERLING DRUG INC. (US) 1989-08-29 US disclosed
EP-0322164-A2 Ethanolamine derivatives GLAXO GROUP LIMITED (GB) 1989-06-28 EP disclosed
EP-0207454-A2 Isoxazole and furan derivatives, their preparation and use as antiviral agents STERLING WINTHROP INC. (US) 1987-01-07 EP disclosed